One person was killed and three others were wounded in the shooting at the Poway synagogue, authorities said Saturday.
"Best I can tell you at this point is that we had four folks with gunshot wounds, we do have one fatality", Poway Mayor Steve Vaus said.
In Los Angeles, police said they were closely monitoring the synagogue shooting in Poway and "communicating with our local, state and federal partners".
It is being advised to stay clear of the area to allow deputies to investigate. "We're looking into digital evidence and checking the authenticity of an online manifesto", the department said in a tweet.
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Derryl Acosta, a spokesperson at Palomar Medical Center, said that the hospital's trauma center in Escondido, California, was expecting at least one patient and that one to four additional patients might be on the way.
Authorities later identified one of the victims as the rabbi, who underwent surgery for treatment of "defensive wounds to his index fingers". The three others - a girl and two men - were in stable condition with non-life-threatening injuries, he said.
It is the last day of Passover and the synagogue had advertised on Facebook a service starting at 11am.
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U.S. House Speaker Nancy Pelosi and California Gov. Gavin Newsom offered their condolences to the Jewish community after a man opened fire Saturday at a synagogue outside San Diego.
Gore said he couldn't provide a motive while investigators interrogate the shooter, who is white. He said he heard a total of 15 shots and that the shooting lasted between 20-30 seconds. Seven people were praying in the mosque at the time the early morning fire broke out, but they were quickly able to extinguish it. The poster described himself as a nursing school student and praised the suspects accused of carrying out deadly attacks on mosques in New Zealand last month and at Pittsburgh's Tree of Life synagogue October 27.
President Donald Trump sent the community his "thoughts and prayers" after the shooting.
In light of the attack, local police also closed a number of roads and advised worshipers who became separated during the shooting to go to The Family Assistance Center at Poway High. God bless you all.
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Mr Biden is one of the favourites to become the Democrat nominee for president and take on Trump in next year's election. In retrospect, he said, he should have held a hearing "where the tone and questioning was not hostile".
Outgoing Diaspora Affairs Minister Naftali Bennett said he was closely watching the situation and thanked law enforcement for their speedy response.