With another game at City on Saturday in the Premier League, Pochettino says there's no time to reflect.
"Spurs don't have the biggest squad in the world and the other night will have taken a lot out of them".
Defeat may prove costly for third-placed Spurs who are struggling to hang on to their top-four place.
"Season after season, his game has evolved, all the things he does now".
Son Heung-min had already forced Ederson in a smart save from a narrow angle before City scored and the Brazilian goalkeeper had to rush from his goal once more to deny Christian Eriksen an equaliser on 15 minutes.
He said: "Both teams have incredible players with heart and personality. Now in different circumstances because City needs to win to stay top of the league", Mourinho told Russia Today.
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But referee Michael Oliver waved away the protests. The story of their Champions League campaign so far is stuff movies are made of. "After injury they don't train properly to be able to take a game every three days".
After the seven-goal thriller in midweek, it looked as though we were in for another goal fest after just five minutes.
The hosts have a winning streak of nine successive Premier League matches. That was the story of the first half for Spurs, the half-chances that didn't fall but considering the line-up Spurs had to feel pretty good overall.
Having been at home first against Bayern and Porto, the Reds will head to the Camp Nou for the first leg on May 1. We were close at the end. "Nothing has changed since July - we are in it, and now we want to win it".
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What's going wrong for the Manchester City midfielder?
Spurs boss Mauricio Pochettino is still anxious about VAR, despite the system sending his side through to the Champions League semi-final.
Ahead of the game, Pochettino explained that the Spurs captain had picked up a minor injury and was not risked in the clash against City.
Sergio Aguero put City in command of the tie after the break but Fernando Llorente swung it back in Spurs' favour when bundled in another goal from a corner after 73 minutes. "It's a pity, because now we arrive in the best moment of the season and we are going to miss him for these four days and maybe the FA Cup, but we'll see tomorrow [Sunday]".
It's awesome that Spurs are in the last four without adding to their squad and while also coping with so many injuries.
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Liverpool are set to pocket a £80million windfall for reaching the Champions League semi-finals, based on confirmed Uefa figures. Liverpool breezed past Porto , as expected, with a 4-1 victory away from home to win 6-1 on aggregate.