Zarif's online comments are the latest in the escalating war of words between Washington and Tehran.
Iran's Foreign Minister Javad Zarif shrugged it off in his own tweet Monday afternoon: "COLOR US UNIMPRESSED: The world heard even harsher bluster a few months ago".
The tweet followed a speech by the Iranian president earlier on Sunday in which he warned, "Mr Trump, don't play with the lion's tail, this would only lead to regret", according to state news agency IRNA.
Iran experts are unsure if the 280 character-limit broadsides are more likely to foreshadow conflict or if they are a way to project strength before engaging Tehran diplomatically.
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He cited the harsh words between the US and North Korea that preceded the high profile summit between Trump and North Korean leader Kim Jong Un and denuclearization talks. "This will take you nowhere", he said.
"He's much more impulsive than he is strategic".
Trump's national security adviser John Bolton is a supporter of the MEK.
He says: "Iran has said very clearly that any war with them will be very costly, and this means American bases throughout the region could be a target".
"There is no need for us to respond to any nonsensical comment and answer back to them", he said. She declined repeated questions about whether Trump would consider meeting with Rouhani.
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Meanwhile US defence secretary Jim Mattis, while speaking at a news conference in California, listed his concerns about Iranian actions in the Middle East, including Tehran's support for Syrian President Bashar al-Assad in the ongoing civil war and for Yemen's Houthi militants fighting against the "internationally recognized government".
The other signatories to the deal, including France, the United Kingdom and Germany, have vowed to stand by it.
Iran has faced the threat of U.S. sanctions since Trump decided in May to withdraw the United States from a 2015 agreement between world powers and Iran over its disputed nuclear program.
"Right now, the United States is undertaking a diplomatic and financial pressure campaign to cut off the funds that the regime uses to enrich itself and support death and destruction", Pompeo said in his speech at the Ronald Reagan Presidential Library and Museum in Simi Valley.
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